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Despite misconceptions held by some people, anal sex risks are not just an issue for gay men. Anal chlamydia and gonorrhea are here to debunk the common myth that when sexually transmitted diseases strike, your vagina will let you know. Anal sex is any type of sexual activity that involves the anal area. Whether you are thinking of having anal sex for the first time, or you just want more information on how to stay safe and enjoy it, this page will help answer your questions. keywords sexually transmitted diseases, anal ulcerations, proctitis there are over 15 million cases of sexually transmitted diseases (stds) annually in the united states and the etiologic agents for these infections exceed 25 in number. 1 the symptoms of any particular sexually transmitted disease are largely dependent on the route and site of infection. the only way to avoid stds is to not have vaginal, anal, or oral sex. If you are sexually active, you can do the following things to lower your chances of getting an std being in a long-term mutually monogamous relationship with a partner who is not infected with an std (e. , a partner who has been tested and has negative std test results). anal sex is the highest-risk sexual behavior for hiv transmission. Vaginal sex has a lower risk, and activities like oral sex, touching, and kissing carry little to no risk for getting or transmitting hiv. The vast majority of men who get hiv get it through anal sex.