Surgical treatment for anal intraepithelial neoplasia

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  anal squamous cell cancer is an uncommon malignancy caused by infection with oncogenic strains of human papilloma virus. Anal cancer is much more common in immunocompromised persons, including those infected with human immunodeficiency virus.   anal intraepithelial neoplasia (ain) is a premalignant lesion for anal cancer. , human papilloma virus (hpv)human immunodeficiency virus infections, post-organ transplantation patients, and men who have sex with men) and development is driven by hpv infection. Anal intraepithelial neoplasia (ain) may be precursive for scc, and screening cytology with referral of persons with abnormality for high-resolution anoscopy-guided biopsy, and ain treatment, has.   a population based, case-control study has shown that anal intraepithelial neoplasia is strongly associated with hpv infection. 3 it can present as part of a multifocal disease process involving any or all sites of anogenital cancer. 13 there are aetiological and clinical parallels between anal intraepithelial neoplasia, vulval intraepithelial neoplasia, and cervical intraepithelial neoplasia. A multidisciplinary approach must be used in the management of anal cancer, including oncologists, general surgeons, radiologists, and specialist nurses. Chemo-radiotherapy is often the first choice treatment for anal tumours (expect from t1n0 carcinomas, whereby wide local excision surgical treatment is usually sufficient). Cervical intraepithelial neoplasia (cin), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. More specifically, cin refers to the potentially precancerous transformation of cells of the cervix. Cin most commonly occurs at the squamocolumnar junction of the cervix, a transitional area between the. The lesions under this term have been previously known as bowen disease, anal intraepithelial neoplasia (ain) i, ii, and iii, anal dysplasia, and scc in situ. 30 based on current guidelines, 30 it has been recommended that these should be classified as either (1) low-grade squamous intraepithelial lesions (lsils) or (2) high-grade squamous intraepithelial lesions (hsils). Anal intraepithelial neoplasia (ain) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer. 2011 the authors 8 colorectal disease 2011 the association of coloproctology of great britain and ireland.

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